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HLA (Human Leukocyte Antigens)

By Dean Goodless, M.D., About.com

Updated: November 1, 2007

About.com Health's Disease and Condition content is reviewed by Casey Gallagher, MD

Definition: Cell markers that appear on the surface of white blood cells and aid the immune system in normal functioning. The markers are encoded by genes in human DNA. Certain HLA markers are more commonly found in those people prone to autoimmune diseases, such as rheumatoid arthritis, ankylosing spondylitis and psoriasis.
Also Known As: MHC (Major Histocompatability Complex)
Examples: Human leukocyte antigen typing can be used to determine an individual's susceptibility to certain diseases.

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